Sepsis Clinical Guide

Sepsis is a serious systemic infection that can quickly lead to circulatory shock, organ failure and death if inappropriately treated. It is also a serious problem in hospitals throughout the US and the world. In 2013, 1.3 million people were admitted to US hospitals for sepsis (#1 cause of index admissions!) at a total cost to the US healthcare system of $23.7 billion dollars (#1 most expensive condition!). Over 250,000 people die of sepsis in the US every year, more than from prostate cancer, breast cancer and AIDS combined. Despite its large toll on public health, public awareness of this condition is poor and the quality of treatment is highly variable often due to late recognition and treatment.

In sepsis, time is of the essence. Successful treatment hinges on prompt recognition of symptoms, correct antibiotic administration, and hemodynamic stabilization. Lack of appropriate sepsis management knowledge at the bedside leads to delayed symptom recognition, serious complications, medical errors, increased treatment costs, and avoidable morbidity and mortality. For this reason, we created this app to provide busy health professionals with essential management information based on the latest practice guidelines in a format that is easily accessible at the point of care.

The Sepsis app features search, annotation, bookmarking functions and calculator support. All content is extensively referenced and footnoted where appropriate, and periodically updated. This app remains free of charge due to the generous sponsorship of Beckman Coulter.

Clinical topics covered in the Sepsis app include:

- The latest definitions and clinical guidelines including Sepsis-3 and the 2016 Surviving Sepsis Campaign (SSC) guidelines

- Epidemiology, risk factors and pathophysiology of sepsis and septic shock

- Common differentials and etiology, guidelines on performing appropriate H&P and workups

- Management of common causes including hospital-acquired pneumonia (HAP), ventilator-acquired pneumonia (VAP) and intra-abdominal infections

- Sepsis management bundles, early goal-directed therapy, hemodynamic management, adjunctive therapies, mechanical ventilation of sepsis-induced ARDS, and other essential management guidelines from the SSC and the American Thoracic Society (ATS)

- Antibiotic therapy including specific guidelines for the treatment of HAP from ATS and the Infectious Diseases Society of America (IDSA)

- Diagnosis and management of pediatric and neonatal sepsis including the management of pediatric fever, important differences from management of sepsis in adults, management of sepsis-induced persistent pulmonary hypertension of the newborn (PPHN), empiric antibiotic treatment recommendations for GBS infections, interventions in pediatric septic shock, and other pediatric-specific information

- Important calculators including the Sequential Organ Failure Assessment (SOFA), quick-SOFA, APACHE II, Multiple Organ Dysfunction Score (MODS), the Simplified Acute Physiology Score (SAPS) II, the National Early Warning Score (NEWS), the Clinical Pulmonary Infection (CPI) score, the Inferior Vena Cava Collapsibility Index, and others

- Drug administration information including antibacterial and antifungal antibiotics, adrenergic and other vasoactive agents, corticosteroids and diuretics

Recommended by:

- Top US doctors on HealthTap

- MDLinx.com

- imedicalapps.com

- The Russian Sepsis Forum (sepsisforum.ru)

- The ED Trauma Critical Care Blog (edtcc.com)

Sepsis adalah infeksi sistemik serius yang cepat dapat menyebabkan syok sirkulasi, kegagalan organ dan kematian jika tidak tepat diobati. Ini juga merupakan masalah serius di rumah sakit di seluruh Amerika Serikat dan dunia. Pada tahun 2013, 1,3 juta orang dirawat di rumah sakit untuk sepsis (# 1 penyebab penerimaan Indeks!) AS dengan total biaya untuk sistem kesehatan AS $ 23,7 miliar dolar (# 1 kondisi paling mahal!). Lebih dari 250.000 orang meninggal dari sepsis di AS setiap tahun, lebih dari dari kanker prostat, kanker payudara dan AIDS digabungkan. Meskipun tol besar pada kesehatan masyarakat, kesadaran masyarakat dari kondisi ini adalah miskin dan kualitas pengobatan sangat bervariasi sering karena terlambat pengakuan dan pengobatan.

Pada sepsis, waktu adalah esensi. Keberhasilan pengobatan bergantung pada pengakuan yang cepat dari gejala, pemberian antibiotik yang benar, dan stabilisasi hemodinamik. Kurangnya pengetahuan manajemen sepsis tepat di samping tempat tidur mengarah ke pengakuan tertunda gejala, komplikasi serius, kesalahan medis, peningkatan biaya pengobatan, dan morbiditas dihindari dan kematian. Untuk alasan ini, kami menciptakan aplikasi ini untuk memberikan sibuk profesional kesehatan dengan informasi manajemen penting berdasarkan pedoman praktek terbaru dalam format yang mudah diakses di titik perawatan.

The Sepsis aplikasi fitur pencarian, penjelasan, fungsi bookmark dan dukungan kalkulator. Semua konten secara luas dirujuk dan catatan kaki di mana yang sesuai, dan diperbarui secara berkala. Aplikasi ini tetap gratis karena sponsorship murah hati Beckman Coulter.

topik klinis yang tercakup dalam Sepsis aplikasi meliputi:

- Definisi terbaru dan pedoman klinis termasuk Sepsis-3 dan 2016 Bertahan Sepsis Campaign (SSC) pedoman

- Epidemiologi, faktor risiko dan patofisiologi sepsis dan syok septik

- perbedaan umum dan etiologi, pedoman melakukan sesuai H & P dan workups

- Pengelolaan penyebab umum termasuk didapat di rumah sakit pneumonia (HAP), ventilator-acquired pneumonia (VAP) dan infeksi intra-abdomen

- bundel manajemen Sepsis, awal diarahkan pada tujuan terapi, manajemen hemodinamik, terapi ajuvan, ventilasi mekanik ARDS sepsis-induced, dan pedoman manajemen penting lainnya dari SSC dan American Thoracic Society (ATS)

- Terapi antibiotik termasuk pedoman khusus untuk pengobatan HAP dari ATS dan Penyakit Infeksi Society of America (IDSA)

- Diagnosis dan pengelolaan sepsis anak dan bayi termasuk pengelolaan demam anak, perbedaan penting dari manajemen sepsis pada orang dewasa, pengelolaan hipertensi pulmonal persisten sepsis yang disebabkan dari bayi baru lahir (PPHN), rekomendasi pengobatan antibiotik empiris untuk infeksi GBS, intervensi di anak syok septik, dan informasi anak-spesifik lainnya

- kalkulator Penting termasuk Kegagalan Sequential Organ Assessment (SOFA), cepat-SOFA, APACHE II, Beberapa Disfungsi Organ Score (MODS), yang Sederhana akut Fisiologi Score (SAPS) II, Dini Nasional Peringatan Score (NEWS), yang Paru Klinis infeksi (CPI) skor, yang inferior Vena Cava collapsibility Index, dan lain-lain

- Informasi Pemberian obat termasuk antibakteri dan antibiotik antijamur, adrenergik dan agen vasoaktif lainnya, kortikosteroid dan diuretik

Direkomendasikan oleh:

- dokter Top AS pada HealthTap

- MDLinx.com

- imedicalapps.com

- Rusia Sepsis Forum (sepsisforum.ru)

- The ED Trauma Critical Care Blog (edtcc.com)